Peripheral T-cell Lymphomas

The peripheral T-cell leukemias (and the NK lymphomas which are rare in the US and Europe, but common in Asia) together comprise about 15% of NHL.

1. Peripheral T-cell Lymphoma, Unspecified

This is a wastebasket category. Morphologically, all different cells sizes are present.

2. Adult T-cell Leukemia/Lymphoma

This disease occurs in Japan and the Carribbean, and is associated with HTLV-1 infection of CD4 positive cells. It is characterized by skin lesions, lymphadenopathy and hepatosplenomegaly. It is often rapidly fatal. Morphologically, lymphocyte nuclei are cloverleaf or flower shaped.

3. Cutaneous T-cell neoplasms

A. Mycosis fungiodes. Cutaneous lesions proceed from plaques to tumors. Nuclei are cerebriform.
B. Sezary Syndrome: Exfoliative erythroderma, associated with leukemia.

Lymphomas

Heme-Onc

Net Scut Home

Please direct all comments to:

Last modification: April 30, 1999