Transfusion Complications

Blood Borne-Infections

• Viruses
• Hepatitis A, B, C, perhaps others
• AIDS
• HTLV I/II
• Cytomegalovirus
• EBV
• parvovirus
• Jakob-Creutzfeldt (?)
• Protozoa
• Malaria
• Babesia
• Chagas Disease
• Spirochetes
• Syphilis
• Lyme Disease
• Relapsing Fever
• Rickettsiae
• Rocky Mountain Spotted Fever
• Q fever
• Bacteria
• Brucellosis
• Yersinia

• Red blood cells
• Immediate hemolytic reactions
• Delayed hemolytic reactions
• White cells
• Chill/fever reaction
• GVHD
• Platelets
• Refractoriness
• Chills, fever, hypotensive reactions
• Post-transfusion thrombocytopenic purpura
• Plasma
• Urticaria
• Anaphylaxis

• Contaminated blood (endotoxin)
• Circulatory overload
• Air embolism
• Hemochromatosis
• Massive transfusion effects
• Hypothermia
• Citrate toxicity
• Acid-base changes
• Potassium imbalance
• Hemostatic abnormalities