Additives

Acetate1 mEq/g protein/kg.  Used as a buffer.  Given as sodium or potassium salt.  Order the same number of mEq of acetate as g/kg protein, more if the infant is acidotic.
Cysteine:  Can be added to TPN as 40 mg/gram amino acids, prn.  To decrease pH in order to increase the solubility of calcium and phosphate.  If acidotic, add more acetate.
Carnitine10-25 mg/kg/day (greater than 28 mg/kg/day can impair growth).  For triglycerides greater than 150mg/dL.  Deficiency can alter fat metabolism.
Zinc:  Recommended Zinc intake is 150 mcg/kg/day for term, and 400 mcg/kg/day for preterm infants.  Maximum of 1000 mcg/kg/day.  note that 0.2 ml/kg of neotrace provides 30 mcg/kg/day of zinc.
Insulin:  Used to improve glucose tolerance when hyperglycemia prevents GIR from advancing greater than 5 mg/kg/minute.
Albumin:  TPN dose = 1 g/kg/day for about 4 days.  Used to sustain oncotic pressure when hypoalbuminemic (less than 2.4).  Not acute treatment.


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