DNA-Interactive Drugs: Leucanthone


 
Name Leucanthone 
Miracil D
Category Thioxanthone
Binding Mode Intercalation
Site Specificity A/T preference by DNase I footprinting [Bailly, 1993]
Effect on DNA Unwinds DNA 15o [Bailly, 1993 #717]
Preparation and Use Prepared as a 5 mM stock in DMSO
 
DNA drugs
Heme-Onc
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Please direct all comments to: Jack Welch, M.D., Ph.D.
Last Modified August 1, 1998