
| Name | Menogaril
7-OMEN 7(R)-O-methylnogarol U-52047 TUT-7 |
| CAS# | 71628-96-1 |
| NCS# | 269148 |
| MW | 541.54 (MSDS from Upjohn) |
| Category | Anthracycline |
| Binding Mode | Presumed to be intercalation, although interaction with DNA is much weaker than with parent nogalamycin [Li, 1979] |
| Site Specificity | Unknown |
| Effect on DNA | Increases duplex Tm slightly, weak DNA interaction by CD analysis [Li, 1979]. |
| Preparation and Use | Dissolve in DMSO, heat to 37oC in water bath, vortex into solution. |
| DNA drugs |
| Heme-Onc |
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