DNA-Interactive Drugs: Bisantrene


 
 
Name Bisantrene 
(9,10-anthracenedicarboxaldehyde bis[(4,5-dihydro-1H-imidazol-2y)hydrazone] 
Anthracenedione acetate
NCS 337766
MW 348.47
Category Anthracenedione (aminoalkylanthracene)
Binding Mode Intercalation
Site Specificity DNA unwinding activity [Bowden, 1982]
Preparation and Use 5mM stock prepared in DMSO
 
DNA drugs
Heme-Onc
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Please direct all comments to: Jack Welch, M.D., Ph.D.
Last Modified August 1, 1998