Infants are as
capable of pain and suffering as adults no matter what their gestational
age and weight
A good general
guideline is to treat pain with analgesics, and treat agitation with sedatives
(if treatment is indicated).
Common analgesics
used in the NICU include:
Fentanyl: A potent narcotic. Dose is 1 - 3 mcg/kg IV.
If patient is extubated, watch respiratory status closely since apnea is
commmon. This is a great drug for procedures like chest tube placement,
and is often used during ECMO. May be reversed with naloxone at
0.1 - 0.2 mg/kg IV/ET/IM.
Morphine: Less potent but longer lasting than fentanyl. Dose
is 0.05 - 0.2 mg/kg IV. Also a potential cause of apnea, and also
reversible with naloxone.
Tylenol: May be used for mild pain in the infant with established
enteral intake. Dose is 15 mg/kg PO/PR. Liver toxicity is rare
at normal dosages.
Common sedatives
in the NICU include:
Midazolam (Versed): A potent short acting benzodiazepine. May
cause respiratory depression or hypotension, so monitor patient closely
during use. Usual dosage is 0.05 - 0.1 mg/kg IV/IM.
Chloral Hydrate: Occasionally used in older infants with established
enteral intake. Dose is 25-50 mg/kg PO/PR. Not useful for painful
procedures, but great for CT scans and BAER screens.